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additional downsides include kidney stones[1,2,3,4], bone mineral loss[5] and a long list of other complications (including death):

https://www.thepaleomom.com/adverse-reactions-to-ketogenic-d...

1. https://pubmed.ncbi.nlm.nih.gov/11095028/

2. https://pubmed.ncbi.nlm.nih.gov/10893623/

3. https://journals.sagepub.com/doi/pdf/10.1177/088307380730192...

4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852806/

5. https://pubmed.ncbi.nlm.nih.gov/19064531/



Firstly those studies are all in children..

Study 1 doesn't actually show increases in kidney stones.

Study 2 has N of 4...

Study 3 looks reasonable, though they did note "use of oral potassium citrate significantly decreased the prevalence of stones" which is good news!

Study 4 has N of 25 & no info about what they actually ate other than macronutrient ratio.


> Firstly those studies are all in children

Your point? the OP ended his sentence with "especially in children" so I thought I'd share that which was relevant to children. If you are looking for information on adults, here are some possible clues:

https://www.nature.com/articles/pr19971830

It makes sense considering the increase in uric acid, but might only be a problem in children and those susceptible to kidney stones (although when it presents in children, that is some pretty important information in terms of holistic, long-term diet considerations). Still definitely worth mentioning and I'm sure we will get more information as more studies are done on adults (most are on children due to it being used as an epilepsy treatment)




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