Yes, but the job market sucks there, especially if you don't want to work in Defense. :) If you want to live where life is remotely walkable (a la San Francisco), the prices jump considerably. A decent house in a decent neighborhood comfortably around downtown will run 300k. Making half what you do in SF and paying 300k isn't so grand.

I love Tucson. I grew up there. It's just a bad place to be a software developer.