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Honest question: isn’t all inheritance transgenerational?


No, you may have certain inheritance mechanisms that can only last for one or two generations. This is typically related to the fact that female mammals are born with all of the egg cells that they will ever have. So, any direct stressor applied to the mother during her life could affect her children & grandchildren (intergenerational), but it won't affect subsequent generations (transgenerational).

The way this can work is that stressors to the mother's organism can affect the development of children, especially stressors to a pregnant mother - so transmission to the next generation is clear (e.g. a starving pregnant mother may have more sickly children). Then, for daughters, their eggs may be directly impacted by this stressor, so that their own children, which come from those egged, may be impacted. However, these children won't carry any trace of that stressor, unless it is genetic in nature.


Sure, but epigenetics is inheritance that does not have an associated genetic sequence change. The DNA sequence is identical.


There's also horizontal (intergenerational) gene transfer, though you might not call that "inheritance".




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