Its funny for me, born and raised in the endless river valleys of the PNW, that I am so used to this topology that I'm much more comfortable in cities with an "opposite valley wall" (even if it's a building facade on the other side of the street and not the next row of hills a couple miles distant) in sight, than I am in Florida, on islands, or other big flatlands areas with nothing at all to break up the great sweep of the horizon.
I'm the opposite, I'm always more at ease in the great plains (I'm from Eastern-Europe, for context), while when I'm at the mountainside I feel like there's something that's just about to "fall on my head" or similar, something that hangs over me.