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I know there are some extreme cases reported where antidepressants were associated with seizures, but from what I understand that's extraordinarily rare. I don't just mean it's rare in clinical trials and research. None of the physicians I've worked with have seen changes in seizure activity following years of SSRI use. The research in that area has also seemed to have petered out without an obvious mechanism or associated population to further explore.

The closest thing I can think of is high dose stimulants causing tonic clinic seizures, but I'd be curious if the unintentional hyperactivity of neurons in stimulants is physiologically similar to increasing oscillatory activity.

I'm not an expert in antiepileptics though so it'd be nice to get some more perspectives here



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