Test your code against Firefox. I've encountered many bugs (mostly small and non-breaking issues) in major enterprise SPAs which happened because the developers only did their stuff in Chrome. Little things, like spans acting as check-boxes (why?) only being selectable via keyboard, or custom tool tips not aligning with elements come to mind. But also breaking issues, like using APIs that only just landed in Chrome or assuming the non-standard behavior of the Chrome behavior is the actual standard across all browsers.