We use htmx (mostly via our django-livecomponents) on our production website, for several public facing features. We've initially replaced numerous small things that were built with Alpine before, and once we've gained confidence we rewrote our whole messaging app from reason/react app.

Fun thing, customers find the new version (htmx/django-livecomponents) to be more responsive than the old version (react+REST). New version is less lines of code and easier to hack on die to fewer context switching.

Give htmx a try, it's worth a shot!