There's a "profit spectrum". On the one side of it are money hungry wall-street bankers, who for them profit is the only motive all else be damned.

On the other side of the spectrum, there are non-profit companies. Some live without profit, based on donations, Others live as a "social corp" where all profits go to scale up growth, while keeping their main motive a non profit goal. Some of those non-profits can create huge changes.

In the middle you can also find lifestyle entrepreneurs. For many of those profit is not the main motivation.

So yes, there are successful entrepreneurs who are not motivated mostly by profit.