A special ergonomic mouse -- the kind a couple of my colleagues had on medical advice after some RSI issues -- costs almost $500.
For vanity, see the standard Apple keyboard, which costs about $200.
I wound up on the ErgoDox EZ due to wrist and arm pain that it helped significantly.
All of those features contributed to the pain reduction, as far as I can tell (based on the slow series of keyboard changes I went through).
This is not a rhetorical question - if there's a significantly cheaper option that meets my needs, I want to know.