Kind of different. Using my example of the frontend interview track as an example, they would ask you something like:
"implement a custom event emitter class in JavaScript" or "implement an image carousel component"...
...instead of something like "invert a binary tree".
Plus you'd get 2-3 rounds of these questions in lieu of the leetcode DS&A rounds. The (usually single) system design round would remain the same (albeit being something like implementing a UI component at a high and holistic level).