The paper (I'm sure it's been posted somewhere in thread). Surprisingly readable (if you have a basic understanding of immunology and Google), go check it out.
The TL;DR is they administered the vaccine to many people and compared the immune response, as measured by various immunology assays, and it elicited a noticeable response for every assay very close to the same responses from actual COVID patients. There were plenty of mild to moderate side effects, but they were reduced quite a bit using paracetamol (Tylenol, basically)
The paper (I'm sure it's been posted somewhere in thread). Surprisingly readable (if you have a basic understanding of immunology and Google), go check it out.
The TL;DR is they administered the vaccine to many people and compared the immune response, as measured by various immunology assays, and it elicited a noticeable response for every assay very close to the same responses from actual COVID patients. There were plenty of mild to moderate side effects, but they were reduced quite a bit using paracetamol (Tylenol, basically)