> I don't understand anything about biology/vaccines or anything else relevant - but there have been several stories in history of medicine that was thought to have no side effect, that ended up being taken off the shelves because it was more dangerous than first thought.
That’s the entire point of a Phase one trial. Vaccine studies may be a little different in their numbering, but the intent of a phase one trial is to figure out if the treatment is safe. The effectiveness is a separate question.
Yes. It worked out so well the last pandemic (2009 swine flu). The vaccine had no side effects in the trials (healthy people 20-55), but caused narcolepsy for children, leaving them disabled for life. This affected over 500 children in Sweden and Finland, and an unknown number across the world.
That’s the entire point of a Phase one trial. Vaccine studies may be a little different in their numbering, but the intent of a phase one trial is to figure out if the treatment is safe. The effectiveness is a separate question.
https://www.cdc.gov/vaccines/parents/infographics/journey-of...