I doubt it would be any more profitable in the long run. A Mars colony would have extremely high barriers to trade. It's like a permanent trade embargo. Countries don't do well without trade. An entirely self-sufficient, technically advanced community hasn't been done, even on Earth.

Antarctica would be much easier and cheaper in comparison.

I don't understand why some people say they want to live on Mars. They'd be confined in small metal boxes, surrounded by things that would kill them in a moment. The cost of everything would be enormous, if it was available at all.

If you want that experience, you can get it now on Earth in places we call "prisons".