It looks interesting but a bit spooky. A real editorial board would have dozens of action editors. They only require a single review, and it's not entirely clear what the process is. They also permit rubriq, which has ill-defined measures for review quality and payment, kind of amazing given that it's wading into an area of very problematic ethics.
This doesn't feel like a major player yet, but what do I know, I'm not in medicine. In my field, reputable open journals would be things like PLOS One, JMLR, and JAIR.
What do you think of Wikiversity's Journal of Medicine? It's a decent stab at a reputable open journal:
http://www.wijoumed.org/