Disclaimer: I am not a doctor, please do not take this advice as infallible and especially please do not mix medication that is self administered based solely off of the following paragraph.
I don't think OP is suggesting they be taken at the same time. The answer to the question however is that would depend on the stimulant being ingested. If it is an amphetamine like adderall, there isn't that much cross interaction in their pharmacology. Adderall (amphetamines) in ADHD medication based doses primarily act in increasing dopamine in between neurons while psilocin is primarily acts on serotonin and its receptors. While there might be some compounding sympathetic nervous responses at standard therapeutic doses it is unlikely to cause any noticeable side effects.
At best they might help, at worst, you wasted your money.
PS: Have you tried fish oil (or perhaps algae oil) and zinc? According to the findings I provided, they might help you too.
I have not, only since the latest "health supplements" scam of our time is exactly these kinds of "healthy mushroom boosters". Claiming all kinds of insane health benefits from "mushroom extract" etc. But wrapping it in an earthy Goop-esque marketing cascade targeting rich house-wives and wall street types. You'd be surprised how much BS wall street types fall for (even when something is just priced idiotically high), for instance Molekule air purifiers (literally fake science and work half as well as a $12 HEPA filter) and anything made by Dyson haha.
I am also disappointed with how this "Ask HN" of mine unfolded.
It is perhaps my fault. I should have clarified things from the start.
My intention was to (prematurely?) optimize self-help strategies without medication, but my point wasn't well taken it seems.