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Calling taking a medicine an addiction is strange, sounds like they do not factor in it being a medicine.

For example, those with autism or schizophrenia have a faulty 'fatty acid binding protein 5' (fabp5)[1] which moves endocannabinoids to where they are needed[2]. Flooding the bloodstream with cannabis seems to help[3] by unlocking receptors that would normally be unlocked by endocannabinoids delivered by fabp5.

Obviously this is just one of many health benefits, such as muscle recovery[4] (who would even want that??? bloody addicts i tell ya!)

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240203

2. https://www.buffalo.edu/news/releases/2018/03/013.html

3. https://www.abc.net.au/melbourne/programs/mornings/medicinal...

4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369499


> Calling taking a medicine an addiction is strange

Treating medicine and addictive substances as mutually exclusive categories is much stranger.


Imagine biting this same bullet for benzos and opioids.


There's no reason why it couldn't be both: helping some people while harming others, and perhaps having little effect at all on a third group.


Humans can be allergic to anything - re-read your post replacing 'Psychedelics' with 'nuts' - no-one gets this excited over peanut allergies - we've replaced this fear with education, drugs should be the same.


areweconsolidatedyet is clearly missing from the list


AreWeMetaYet however is there.


Interesting article. Any new emotion or new emotional state creates a new space for new memories, and adolescence provides new emotions. Particular memories are easier to retrieve when in the emotional state they were formed. Maybe this explains why it can be hard to beat depression - pleasant memories are more difficult to retrieve and negative emotions easily surface.

First few times trying weed it felt like micro-tarzan swinging from a familiar branch of neurons to a whole new area of neurons.

Possibly why magic mushrooms and the like are being investigated as a legit therapy.


Depression has quite a few weird effects on memory, e.g. https://en.wikipedia.org/wiki/Overgeneral_Autobiographical_M...


All of them are either wrong or irrelevant because none of them factor in weed helping.


Disappointed in the comments here. There are NO studies involving psychosis and schizophrenia that factor in weed actually helping (hint: it contains an antipsychotic). Schizophrenia involves a defect in the gene responsible for producing the protein FABP5[1] which delivers our bodies naturally produced cannabinoids (eg, Anandamide and 2AG) to where they're needed[2]. Therefore it is not surprising there is a 'link' between those using cannabis and mental illness: flooding the bloodstream with cannabinoids somewhat makes up for the deficit in endocannabinoid delivery.

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240203

2. https://www.wnypapers.com/news/article/current/2018/03/15/13...


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