Cheminformatics is such an example. Heavily used in computational drug discovery.

Computational biology/cheminformatics has probably been on the most frustrating investments pharma companies have made in the past 20 years. There's been waves of optimism with many hires, then a slump after reality doesn't match optimistic expections, and so on. This time it may actually be different, and I myself am in that camp. I'm particularly excited by the discoveries in sampling methods that aren't just molecular dynamics. And the cellular foundation models for pre-screening drug interactions - they aren't quite there yet, but give it time.

The cheminformatics I do (mostly drug discovery/biophysics) definitely requires bonds!

InChI isn't really meant to be used as a format to store 2D molecules say for rendering but rather serves as a unique descriptive chemical identifier. InChI has many flavors but the Standard InChI yields one unique identifier for multiple forms (tautomers) of the same molecule.

This is one of those ghost jobs, the poster keeps posting a job but the job board has been broken all for forever. Someone replied to their prev posting and I even emailed them but received no response.

Ref: https://news.ycombinator.com/item?id=41730044

I've experienced the same with this job specifically. I wish forum mods would crack down on this as it's quite ridiculous

Just a heads up, job postings for jobs based in NYC are now legally required to list a salary range.

TandemAI | Backend Software Engineer | Full-time | NYC preferred | Boston/Remote (US, Canada) | https://tandemai.com/ TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution. We are looking for a Senior Backend Engineer to join our growing Web Applications team. You will actively contribute to back-end initiatives for our cutting-edge computational platform. The candidate, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates the TandemAI molecular physics-based computational platform.

Our stack is Java Spring Boot, Python, PostgreSQL, OpenSearch and we use Slurm to manage most our HPC jobs.

If you have a science background and strong engineering skills this could be an exciting opportunity for you!

If you're interested feel free to email me with subject "Hacker News TandemAI" directly at frederick [dot] parsons [at] tandemai [dot] com

hey Fred, just a heads up - the career page links to a greenhouse board that seems inactive. https://tandemai.com/careers/#currentopening goes to https://boards.greenhouse.io/tandemailimited which says "The board you are looking for is no longer open."

TandemAI | Backend Software Engineer | Full-time | NYC/Boston/Remote (US, Canada) | https://tandemai.com/ TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution.

We are looking for a Senior Backend Engineer to join our growing Web Applications team. You will actively contribute to back-end initiatives for our cutting-edge computational platform. The candidate, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates the TandemAI molecular physics-based computational platform.

Our stack is Java Spring Boot, Python, PostgreSQL, OpenSearch and we use Slurm to manage most our HPC jobs.

If you have a science background and strong engineering skills this could be an exciting opportunity for you!

If you're interested feel free to email me with subject "Hacker News TandemAI" directly at frederick [dot] parsons [at] tandemai [dot] com