I'm in my late 40s, don't remember ever having chickenpox as a child, and I have a choice between getting the chickenpox vaccine now, or waiting til I'm eligible for Shingrix. Having seen friends get Shingles before turning 50 (and boy was it bad), plus watching some of their close family members get chickenpox from contact with them, I kind of want to avoid that stuff. But there's not a ton of expert guidance on whether the right move is to gamble on 50/Shingrix or to get vaccinated now! And when you toss in these dementia concerns, I'm even more confused. I think this would be a different calculation if I was younger, but I honestly don't know what the right move is for someone in my cohort. I decided to wait.

ETA: Someone in comments above points out that the data is still coming in on this question. It looks like the best move is not to ever be exposed to varicella (maybe me?), and the second best move is to be vaccinated with chickenpox, and possibly the ultimate best move is to get Shingrix, but there's a lot of missing data and some timing problems here.